What is Ovagen Peptide & How does it Work?
Ovagen studied for its cell regenerative and cytoprotective properties. It slows down age-related changes by regulating gene expression & protein synthesis. Ovagen is such a natural tripeptide bioregulator that.
- Helps in Liver detoxification
- Restore healthy liver function
- Inhibit HIV replication
- Normalise the digestive tract’s function
Note:
Ovagen peptide should not be confused with another product, Ovagen, that contains ovine (sheep) FSH. These two are not the same and have entirely different functions. At the same time, FSH derivatives promote ovulation in women suffering from PCOS.
Ovagen Components
Ovagen is made up of three main amino acids, which include Glutamyl, Aspartyl, and Leucine (Glu-Asp-Leu). Ovagen components show hydrogen, oxygen, nitrogen, and carbon atoms as building blocks of Ovagen.
The following parameters can represent the chemical identity of Ovagen:
- Molecular Formula: (C15H25N3O8)
- Molecular Weight: 375.37 g/mol
- PubChem CID: 444128
Chemical structure of Ovagen bioregulator
How does Ovagen work?
The anti-aging effect of tripeptides is linked to regulating the vital genes in cells. So, Ovagen peptides also work in the same way.
Let’s explore Ovagen’s mechanism.
- Binding to DNA
Ovagen peptide penetrates cell nuclei, then interacts with DNA and histone protein. This binding helps to modify the chromatin structure by making a stable complex with DNA.
- Reduces aging markers
After binding, it lowers the levels of aging markers like P16, P21, and P53. Its effects can also unlock the genes that were silenced in aging.
- Boost longevity gene
Then it boosts SIRT-6, a key anti-aging gene that repairs DNA & boosts healthy cells in the body.
- Support cell growth
After gene regulation in the cell, Ovagen activates cell proliferation & shows cell rejuvenation.
Mechanism of regulation of gene expression and protein synthesis
Part 2: Ovagen Peptide Benefits
Ovagen peptide works at the cellular level to slow aging, repair organs, & protect against viral damage. Below are the most remarkable benefits of Ovagen that make it a unique and powerful bioregulator peptide.
Let’s explore the key Ovagen peptide benefits that make it effective.
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Slows down cellular aging
Ovagen contributes to a better cellular lifespan. Some of its combined roles do this. These are gene regulation, protein synthesis, and anti-aging pathways.
Ovagen & other short peptides form stable complexes with DNA through molecular modeling. Short peptides, through this modeling, affect gene regulation.
This peptide begins its action by reducing aging markers. To do this, it lowers the levels of P16, P21, and P53. These genetic markers inhibit cell division and accelerate aging. (Khavinson et al. 2014)
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Boosts cellular regeneration
Ovagen helps restore the damaged and stressed cells. This improves their survival and regeneration capacity. This is also valuable in conditions linked to oxidative stress and toxic exposure.
Short Peptides help in the differentiation of stem or pluripotent cells into functional tissues. While this is not always specific to the kidney & liver, it shows that they can regenerate tissue. (Khavinson et al. 2021)
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Reduce the HIV infections.
The most effective fragment, Glu-Asp-Leu, of the Gag-Pol polyprotein inhibits HIV-1 protease. It did not significantly affect normal mammalian proteases such as pepsin.
Ovagen peptide inhibits the HIV-1 protease, an enzyme essential for viral replication. This way, Ovagen may help slow HIV replication in lab studies, though it is still under research. (Louis et al. 1998)
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Regulate gene expression
The key benefit of Ovagen peptide is its ability to regulate gene expression. By interacting with DNA, Ovagen can activate & suppress the genes to maintain balance.
This balance ensures proper cell growth, repair, & stability, especially in the liver & kidneys. (Khavinson et al. 2014)
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Kidney regeneration & well-being
One of the most remarkable benefits of Ovagen peptide is its positive effect on kidney health. Ovagen helps maintain strong kidney function even under aging and toxic conditions.
It enhances the natural detoxification function of the kidneys, allowing them to filter waste more efficiently. The diuretic effect of Ovagen increases urination & sodium extraction. It supports a healthier water-salt balance without harming the kidneys’ filtration system.
This makes it a promising peptide for anyone interested in kidney protection, regeneration, and long-term well-being. (Zamorskii et al. 2019)
Part 3: Ovagen Peptide Dosage
Ovagen peptide dosage can be estimated from an experimental study in the lab. In this experiment, 4 peptides were used on 35 old rats for the treatment of chronic kidney disease (CKD). The peptide dosages used are:
- Polypeptide Kidney Complex (PKC): 300 µg/kg
- Peptide EDL (Ovagen): 3 μg/kg
- Peptide AED: 3 µg/kg
- Peptide AEDG: 7 μg/kg
The peptides were injected daily for 10 days. Kidney functions were measured through urine tests, sodium balance,& antioxidant activity. From this experiment, Ovagen peptide dosage has been estimated to be 3 μg/kg.
Part 4: Ovagen Side Effects
Ovagen is still under observation. It has been well tolerated, yet no large side effects have been seen. But in early lab tests or animal models, some mild effects have been noticed. These may include:
- Headaches
- Discomfort in digestion
- Irritation at the injection site (for the injectable form)
- Poor in vivo stability
- Poor permeability in the membrane (Wang et al. 2022)
Note:
Peptide users sometimes also mention minor stomach disturbance, like diarrhoea or burning. Even if this happens, it also represents mild side effects.
Is Ovagen reliable?
Yes, Ovagen is considered reliable only in research settings. The reason for its reliability is that it was developed by researchers in the lab & promised for human well-being. It even inhibits viral replication—without significant side effects in experimental models. But it is still used for research purposes only.
What makes Ovagen reliable:
- Strong scientific background: Developed by the Khavinson peptide school of thought. It is also tested in labs for animal studies.
- Ovagen peptide benefits: Its powerful immune-boosting, anti-aging, and cytoprotective properties make it very effective.
- Safe in research: Well-tolerated in animal studies, with no significant side effects.
- Trusted suppliers: Companies like NuScience Peptides provide lab-tested Ovagen. It certifies purity standards, making it safer and more consistent for clients.
- Short molecular peptide: Ovagen is a short tripeptide (Glu-Asp-Leu) with a clearly defined formula (C15H25N3O8).
